GS-441524 powder is a highly specialized form of an antiviral medication used to treat Feline Infectious Peritonitis (FIP), a serious and often fatal disease in cats caused by a mutation of the feline coronavirus. As an investigational drug, GS-441524 has shown considerable promise in clinical and practical settings for its ability to halt the progression of this previously untreatable disease.
Injectable Form: When reconstituted into an injectable solution, GS-441524 is typically administered subcutaneously. This route is particularly beneficial for cats with severe gastrointestinal symptoms, as it bypasses the digestive tract and ensures rapid systemic absorption.
Oral Suspension: Alternatively, the reconstituted powder can be given orally, either directly or mixed with food. This method is more convenient for long-term treatment, especially in a home care setting, and is often used for maintenance therapy after initial stabilization with injections.
Clinical studies and anecdotal evidence have demonstrated the efficacy of GS-441524 in treating various forms of FIP, including both the effusive (wet) and non-effusive (dry) forms. Many cats have shown significant improvement, with symptoms such as fever, weight loss, and lethargy resolving over time. In some cases, complete remission has been achieved, offering a new lease on life for cats that were once facing a grim prognosis.
| Property | Details |
|---|---|
| CAS Number | 1191237-69-0 |
| Grade | Pharmaceutcial Grade |
| Shipping Method | Air(UPS, FedEx, TNT, EMS) Or Sea |
| Density | 1.84±0.1 G |
| Appearance | White Powder |
| Storage | Store At Cool Dry Place |
| Molecular Weight | 291.26 |
| Purity |
99.0% |
Diagnosing FIP is challenging and often involves a combination of clinical signs, laboratory tests, and ruling out other diseases. Common diagnostic steps include:
1. Blood tests: Elevated protein levels, high white blood cell count, and low albumin-to-globulin ratio.
2. Imaging: Ultrasound or X-rays to detect fluid accumulation.
3. Fluid analysis: Testing the fluid from the abdomen or chest for elevated protein levels and specific cell types.
4. Biopsy: Histopathological examination of affected tissues can provide a definitive diagnosis.
1. GS-441524 powder is primarily used in scientific research and pharmaceutical development, particularly for studying antiviral treatments. Its main application is in the inhibition of RNA virus replication, making it a crucial compound for investigating viral infections. One of the most well-known applications is in veterinary medicine, where it has been widely studied for its effectiveness against feline infectious peritonitis (FIP), a fatal disease in cats caused by a coronavirus.
2. In laboratory settings, GS-441524 powder is used for drug formulation and pharmacological research, contributing to the development of new antiviral therapies. It has been explored for potential applications in broader antiviral research beyond feline medicine. The compound's bioavailability and efficacy in inhibiting viral RNA-dependent RNA polymerase have made it an essential focus for ongoing studies in virology.
3. Additionally, GS-441524 is utilized in pharmaceutical synthesis for the production of oral and injectable formulations. Researchers and pharmaceutical companies leverage this compound to test and refine treatment protocols, ensuring safe and effective applications in various medical and veterinary contexts.
