GS-441524 powder is a highly specialized form of an antiviral medication used to treat Feline Infectious Peritonitis (FIP), a serious and often fatal disease in cats caused by a mutation of the feline coronavirus. As an investigational drug, GS-441524 has shown considerable promise in clinical and practical settings for its ability to halt the progression of this previously untreatable disease.
Injectable Form: When reconstituted into an injectable solution, GS-441524 is typically administered subcutaneously. This route is particularly beneficial for cats with severe gastrointestinal symptoms, as it bypasses the digestive tract and ensures rapid systemic absorption.
Oral Suspension: Alternatively, the reconstituted powder can be given orally, either directly or mixed with food. This method is more convenient for long-term treatment, especially in a home care setting, and is often used for maintenance therapy after initial stabilization with injections.
Clinical studies and anecdotal evidence have demonstrated the efficacy of GS-441524 in treating various forms of FIP, including both the effusive (wet) and non-effusive (dry) forms. Many cats have shown significant improvement, with symptoms such as fever, weight loss, and lethargy resolving over time. In some cases, complete remission has been achieved, offering a new lease on life for cats that were once facing a grim prognosis.
| Property | Details |
|---|---|
| CAS Number | 1191237-69-0 |
| Grade | Pharmaceutcial Grade |
| Shipping Method | Air(UPS, FedEx, TNT, EMS) Or Sea |
| Density | 1.84±0.1 G |
| Appearance | White Powder |
| Storage | Store At Cool Dry Place |
| Molecular Weight | 291.26 |
| Purity |
99.0% |
Diagnosing FIP is challenging and often involves a combination of clinical signs, laboratory tests, and ruling out other diseases. Common diagnostic steps include:
1. Blood tests: Elevated protein levels, high white blood cell count, and low albumin-to-globulin ratio.
2. Imaging: Ultrasound or X-rays to detect fluid accumulation.
3. Fluid analysis: Testing the fluid from the abdomen or chest for elevated protein levels and specific cell types.
4. Biopsy: Histopathological examination of affected tissues can provide a definitive diagnosis.
GS-441524 powder has gained significant attention for its antiviral properties and is widely used in various scientific and pharmaceutical applications. Below are the key areas where GS-441524 powder is utilized:
1. Veterinary Medicine (FIP Treatment Research) – One of the most prominent applications of GS-441524 powder is in the treatment research of Feline Infectious Peritonitis (FIP), a fatal disease caused by feline coronavirus. Studies have shown its effectiveness in inhibiting viral replication, leading to improved recovery rates in affected cats.
2. Antiviral Drug Development – GS-441524 serves as an essential compound in the research and development of antiviral drugs. It functions as a nucleoside analog, interfering with viral RNA synthesis and showing potential for further drug innovations.
3. Pharmaceutical Formulation – This compound is used in experimental oral and injectable drug formulations, helping researchers develop new therapeutic options for viral infections. Its pharmacokinetic properties make it an attractive candidate for antiviral drug formulation studies.
4. RNA Virus Research – Scientists utilize GS-441524 powder to understand its mechanism of action against various RNA viruses, contributing to broader antiviral research efforts beyond FIP.
5. Pharmacokinetic and Bioavailability Studies – Research institutions use GS-441524 to analyze its absorption, distribution, metabolism, and excretion (ADME) properties, aiding in drug development and improving formulation strategies.
